CSE 307/407: Structural Bioinformatics

Solving problems at the leading edge of medical and industrial technologies depends, in many cases, on improving our understanding of protein function. For example, the debilitating side effects of cancer treatment could be reduced by developing drug molecules that selectively fit the unique structures of cancer proteins. In this case, and in many others, protein shape can yield many deep insights into how proteins function. This course is an exploration, through collaborative and interdisciplinary projects, of the biological, computational, and statistical ideas developed for protein structure alignment, finding functional sites, structure-function inference, molecular surfaces, and evolution in protein structure.